diff --git a/components/radio/index.tsx b/components/radio/index.tsx
index 502e478269..c164867fcc 100644
--- a/components/radio/index.tsx
+++ b/components/radio/index.tsx
@@ -18,9 +18,11 @@ interface CompoundedComponent
   extends React.ForwardRefExoticComponent<RadioProps & React.RefAttributes<HTMLElement>> {
   Group: typeof Group;
   Button: typeof Button;
+  __ANT_RADIO: boolean;
 }
 
 const Radio = InternalRadio as CompoundedComponent;
 Radio.Button = Button;
 Radio.Group = Group;
+Radio.__ANT_RADIO = true;
 export default Radio;
diff --git a/components/tooltip/__tests__/tooltip.test.js b/components/tooltip/__tests__/tooltip.test.js
index 9df5714fc4..62129cd42f 100644
--- a/components/tooltip/__tests__/tooltip.test.js
+++ b/components/tooltip/__tests__/tooltip.test.js
@@ -9,6 +9,7 @@ import DatePicker from '../../date-picker';
 import Input from '../../input';
 import Group from '../../input/Group';
 import Switch from '../../switch';
+import Radio from '../../radio';
 
 describe('Tooltip', () => {
   mountTest(Tooltip);
@@ -402,4 +403,23 @@ describe('Tooltip', () => {
     expect(onVisibleChange).toHaveBeenLastCalledWith(true);
     expect(container.querySelector('.ant-tooltip-open')).not.toBeNull();
   });
+
+  it('should work with disabled Radio', () => {
+    const onVisibleChange = jest.fn();
+    const { container } = render(
+      <Tooltip
+        title="loading tips"
+        mouseEnterDelay={0}
+        mouseLeaveDelay={0}
+        onVisibleChange={onVisibleChange}
+      >
+        <Radio disabled />
+      </Tooltip>,
+    );
+    const wrapperEl = container.querySelectorAll('.ant-tooltip-disabled-compatible-wrapper');
+    expect(wrapperEl).toHaveLength(1);
+    fireEvent.mouseEnter(container.getElementsByTagName('span')[0]);
+    expect(onVisibleChange).toHaveBeenLastCalledWith(true);
+    expect(container.querySelector('.ant-tooltip-open')).not.toBeNull();
+  });
 });
diff --git a/components/tooltip/index.tsx b/components/tooltip/index.tsx
index f72e300fbf..b60f3f8681 100644
--- a/components/tooltip/index.tsx
+++ b/components/tooltip/index.tsx
@@ -87,7 +87,8 @@ function getDisabledCompatibleChildren(element: React.ReactElement<any>, prefixC
   const elementType = element.type as any;
   if (
     ((elementType.__ANT_BUTTON === true || element.type === 'button') && element.props.disabled) ||
-    (elementType.__ANT_SWITCH === true && (element.props.disabled || element.props.loading))
+    (elementType.__ANT_SWITCH === true && (element.props.disabled || element.props.loading)) ||
+    (elementType.__ANT_RADIO === true && element.props.disabled)
   ) {
     // Pick some layout related style properties up to span
     // Prevent layout bugs like https://github.com/ant-design/ant-design/issues/5254